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Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection

Authors :
Arvind Gharbharan
Carlijn C. E. Jordans
Corine GeurtsvanKessel
Jan G. den Hollander
Faiz Karim
Femke P. N. Mollema
Janneke E. Stalenhoef – Schukken
Anthonius Dofferhoff
Inge Ludwig
Adrianus Koster
Robert-Jan Hassing
Jeannet C. Bos
Geert R. van Pottelberge
Imro N. Vlasveld
Heidi S. M. Ammerlaan
Elena M. van Leeuwen – Segarceanu
Jelle Miedema
Menno van der Eerden
Thijs J. Schrama
Grigorios Papageorgiou
Peter te Boekhorst
Francis H. Swaneveld
Yvonne M. Mueller
Marco W. J. Schreurs
Jeroen J. A. van Kampen
Barry Rockx
Nisreen M. A. Okba
Peter D. Katsikis
Marion P. G. Koopmans
Bart L. Haagmans
Casper Rokx
Bart J. A. Rijnders
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

There are currently no drugs available to treat SARS-CoV-2 infection. A promising alternative treatment for COVID-19 patients is convalescent plasma. Here, Gharbharan et al. collect covalescent plasma and report no overall clinical benefit for 86 patients hospitalized for COVID-19 and treated with 300 mL convalescent plasma.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.6dfe323ebd74308ad646da02ba72d20
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-23469-2