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Intraglandular mesenchymal stem cell treatment induces changes in the salivary proteome of irradiated patients

Authors :
Charlotte Duch Lynggaard
Rosa Jersie-Christensen
Morten Juhl
Siri Beier Jensen
Christian Grønhøj
Jacob Melchiors
Søren Jacobsen
Michael Møller-Hansen
Mikkel Herly
Annette Ekblond
Jens Kastrup
Anne Fischer-Nielsen
Daniel Belstrøm
Christian von Buchwald
Source :
Communications Medicine, Vol 2, Iss 1, Pp 1-12 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Lynggaard et al. profile the salivary proteome and metaproteome in patients with head and neck cancer who have received radiation therapy and an intraglandular mesenchymal stem cell (MSC) treatment for radiation-induced xerostomia and in healthy controls. MSC therapy impacts the composition of the salivary proteome in the longer-term.

Subjects

Subjects :
Medicine

Details

Language :
English
ISSN :
2730664X
Volume :
2
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.6dfdb68785ce454eb915038edeb94bf1
Document Type :
article
Full Text :
https://doi.org/10.1038/s43856-022-00223-3