P46 ARTERIAL STIFFNESS IN RELATION TO BIRTH CHARACTERISTICS IN THE JAMAICAN 1986 BIRTH COHORT

Background: We tested the association between birthweight and arterial stiffness measured by aortic pulse wave velocity (PWV) and cardio-ankle vascular index (CAVI) in a birth cohort of 30 year old Jamaicans. Methods: Participants were from the 1986 Jamaica Birth Cohort. Arterial stiffness was measured as PWV using Arteriograph 24hTM and CAVI with VaSeraTM devices. Current anthropometry (height, weight, waist and hip circumference), and brachial blood pressure measures were linked to birthweight and other early life markers of CVD risk (birth-length and maternal height). Linear regression models were used for analysis. Results: Analyses included 235 participants 44% male, with mean±SD age 29.8±0.7years, birthweight 3.1±0.0kg, PWV 6.3±0.1m/s and CAVI 6.3±0.1. Bivariate models showed men had higher arterial stiffness (p < 0.001). Maternal height (p = 0.031), waist/hip ratio (p = 0.019), BMI (p =