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Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis

Authors :
Sanni E. Ruotsalainen
Ida Surakka
Nina Mars
Juha Karjalainen
Mitja Kurki
Masahiro Kanai
Kristi Krebs
Sarah Graham
Pashupati P. Mishra
Binisha H. Mishra
Juha Sinisalo
Priit Palta
Terho Lehtimäki
Olli Raitakari
Estonian Biobank Research Team
Lili Milani
The Biobank Japan Project
Yukinori Okada
FinnGen
Aarno Palotie
Elisabeth Widen
Mark J. Daly
Samuli Ripatti
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

A genome-wide association study identifies MFGE8 as protective against coronary atherosclerosis in European and East Asian populations.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.6dacc6359dd146e9bd207b6e44a8c3fb
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03552-0