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Fetal demise and failed antibody therapy during Zika virus infection of pregnant macaques
- Source :
- Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
- Publication Year :
- 2018
- Publisher :
- Nature Portfolio, 2018.
-
Abstract
- Zika virus (ZIKV) infection in pregnant women has been associated with fetal developmental defects. Here, the authors show that a Brazilian ZIKV isolate causes fetal demise in non-human primates and that antibody treatment at time of peak viremia is insufficient to clear ZIKV replication from amniotic fluid.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 9
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.6ca8c5f99d854de99a13b95f4edccb07
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-018-04056-4