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Cancer detection rates and inter-examiner variability of MRI/TRUS fusion targeted biopsy and systematic transrectal biopsy
- Source :
- Biomedical Papers, Vol 164, Iss 3, Pp 314-319 (2020)
- Publication Year :
- 2020
- Publisher :
- Palacký University Olomouc, Faculty of Medicine and Dentistry, 2020.
-
Abstract
- Background: Software-based MRI/TRUS fusion biopsy depends on the coordination of several steps, and inter-examiner differences could influence the results. The aim of this bicentric prospective study was to compare the detection rates of MRI/TRUS fusion targeted biopsy (TG) and systematic biopsy (SB), and the detection rates of examiners with different levels of previous experience in prostate biopsy. Methods: A total of 419 patients underwent MRI based on a suspicion of prostate cancer with elevated PSA levels. MRI was positive in 395 patients (221 in the first biopsy group [FB] and 174 in the repeated biopsy group [RB]). A subsequent TG, followed by a SB, was performed on these patients by four different examiners. Results: In the detection of clinically significant prostate cancer, a significant difference was found for TG+SB against SB in the RB group (35.1% vs. 25.3%, P=0.047). In the detection of clinically insignificant prostate cancer, the SB had a significantly higher detection rate than TG in both subgroups (FB: 11.9% vs. 4.7%, P=0.008; RB: 13.8% vs. 6.9%, P=0.034). A significant difference was found between the four examiners in the FB for TG (P=0.028), SB (P=0.036), and TG+SB (P=0.017). Conclusion: MRI/TRUS TG in combination with SB had significantly higher detection rates than SB in the RB group only. Differences in detection rates between examiners were dependent on the level of previous experience with TRUS guided biopsy.
- Subjects :
- biopsy
diagnostic imaging
fusion
magnetic resonance
prostate cancer
Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 12138118 and 18047521
- Volume :
- 164
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Biomedical Papers
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.6ca13fe98aea4346bef5f11305841d91
- Document Type :
- article
- Full Text :
- https://doi.org/10.5507/bp.2019.050