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Platelets from patients with visceral obesity promote colon cancer growth

Authors :
Marica Cariello
Elena Piccinin
Emanuela Pasculli
Maria Arconzo
Roberta Zerlotin
Simona D’Amore
Francesca Mastropasqua
Claudia Peres
Giusi Graziano
Gaetano Villani
Graziano Pesole
Antonio Moschetta
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-8 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Platelets from patients with visceral obesity, which highly express miR-19a, can strongly promote colon cancer growth in a xenograft colon cancer model, with miR-19a administration by AAV injection increasing tumor growth.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.6b706cb9b04c89afe9f064abf635cf
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03486-7