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Genetic architecture of host proteins involved in SARS-CoV-2 infection

Authors :
Maik Pietzner
Eleanor Wheeler
Julia Carrasco-Zanini
Johannes Raffler
Nicola D. Kerrison
Erin Oerton
Victoria P. W. Auyeung
Jian’an Luan
Chris Finan
Juan P. Casas
Rachel Ostroff
Steve A. Williams
Gabi Kastenmüller
Markus Ralser
Eric R. Gamazon
Nicholas J. Wareham
Aroon D. Hingorani
Claudia Langenberg
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Finding effective treatments for COVID-19 depends upon understanding genetic regulation of proteins involved in SARS-CoV-2 infection and host response. Here, the authors identify genetic variants linked to expression of such proteins, data which could lead to the discovery of therapeutic targets.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.6b38e315ccef41ffb7a303ba54fecf8c
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-19996-z