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A metabolomics approach for investigating urinary and plasma changes in spontaneously hypertensive rats (SHR) fed with chicken skin protein hydrolysates diets

Authors :
John O. Onuh
Abraham T. Girgih
Ifeanyi Nwachukwu
Shiva Ievari-Shariati
Pema Raj
Thomas Netticadan
Rotimi E. Aluko
Michel Aliani
Source :
Journal of Functional Foods, Vol 22, Iss , Pp 20-33 (2016)
Publication Year :
2016
Publisher :
Elsevier, 2016.

Abstract

Plasma and urine metabolomics profiles of spontaneously hypertensive rats (SHRs) fed with chicken skin protein hydrolysates (CSPHs) were investigated to establish possible biomarkers of blood pressure regulation. SHR and wistar Kyoto (WKY) rats were randomised into groups that received casein-only (control), CSPHs (0.5 or 1%) or chicken skin meal (CSM 1%) diets for six weeks. Results showed that the diets significantly (P

Details

Language :
English
ISSN :
17564646 and 06390412
Volume :
22
Issue :
20-33
Database :
Directory of Open Access Journals
Journal :
Journal of Functional Foods
Publication Type :
Academic Journal
Accession number :
edsdoj.6b0639041244ba3b4742ed393ef40a7
Document Type :
article
Full Text :
https://doi.org/10.1016/j.jff.2016.01.010