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IMF deposition ceRNA network analysis and functional study of HIF1a in yak
- Source :
- Frontiers in Veterinary Science, Vol 10 (2023)
- Publication Year :
- 2023
- Publisher :
- Frontiers Media S.A., 2023.
-
Abstract
- The concentration of intramuscular fat (IMF) is a crucial determinant of yak meat quality. However, the molecular mechanisms that regulate IMF in yak remain largely elusive. In our study, we conducted transcriptome sequencing on the longissimus dorsi muscle tissues of yaks with varying IMF contents. We then filtered differentially expressed genes (DEGs), microRNAs (DEMs), and long non-coding RNAs (DELs) to elucidate potential regulatory pathways of adipogenesis in yaks. Overall, our research sheds light on an array of potential mRNAs and noncoding RNAs implicated in IMF deposition and elaborates on the role of HIF1α in yaks. These findings contribute valuable insights that can serve as a guide for further research into the molecular mechanisms governing IMF deposition.
- Subjects :
- IMF
adipogenesis
RNA-seq
HIF1α
ceRNA
yak
Veterinary medicine
SF600-1100
Subjects
Details
- Language :
- English
- ISSN :
- 22971769
- Volume :
- 10
- Database :
- Directory of Open Access Journals
- Journal :
- Frontiers in Veterinary Science
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.6aa079462fa4ad6aea5abf43c90bab4
- Document Type :
- article
- Full Text :
- https://doi.org/10.3389/fvets.2023.1272238