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Effect of miR-27b on the proliferation and apoptosis of diffuse large b-cell lymphoma cells by targeting the regulation of MET/PI3K/AKT pathway
- Source :
- Discover Oncology, Vol 13, Iss 1, Pp 1-13 (2022)
- Publication Year :
- 2022
- Publisher :
- Springer, 2022.
-
Abstract
- Highlights 1. MET is a direct target of miR-27b. 2. Low expression of miR-27b is correlated with the growth activity of DLBCL cells. 3. miR-27b inhibits the proliferation and invasiveness of DLBCL cells, and promotes the apoptosis of the cells by targeting MET and inhibiting the activity of the MET/PI3K/AKT pathway.
Details
- Language :
- English
- ISSN :
- 27306011
- Volume :
- 13
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Discover Oncology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.69cdd1290e5f4ee689c6f0bfd5cc5b7c
- Document Type :
- article
- Full Text :
- https://doi.org/10.1007/s12672-022-00589-9