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Effect of miR-27b on the proliferation and apoptosis of diffuse large b-cell lymphoma cells by targeting the regulation of MET/PI3K/AKT pathway

Authors :
Rui Zhang
Tianjiao Huang
Jinfeng Li
Hong Zhou
Xuemei Wang
Source :
Discover Oncology, Vol 13, Iss 1, Pp 1-13 (2022)
Publication Year :
2022
Publisher :
Springer, 2022.

Abstract

Highlights 1. MET is a direct target of miR-27b. 2. Low expression of miR-27b is correlated with the growth activity of DLBCL cells. 3. miR-27b inhibits the proliferation and invasiveness of DLBCL cells, and promotes the apoptosis of the cells by targeting MET and inhibiting the activity of the MET/PI3K/AKT pathway.

Details

Language :
English
ISSN :
27306011
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Discover Oncology
Publication Type :
Academic Journal
Accession number :
edsdoj.69cdd1290e5f4ee689c6f0bfd5cc5b7c
Document Type :
article
Full Text :
https://doi.org/10.1007/s12672-022-00589-9