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Pharmacological evaluation of methanolic extract of Cyperus scariosus

Authors :
Wasi Ullah Khan
Rahmat Ali Khan
Mushtaq Ahmed
Latif Ullah Khan
Muhammad Waqas Khan
Source :
Bangladesh Journal of Pharmacology, Vol 11, Iss 2 (2016)
Publication Year :
2016
Publisher :
Bangladesh Pharmacological Society, 2016.

Abstract

The present study is aimed to investigate the phytochemical screening and biological activities of methanolic extract of Cyperus scariosus roots. Dried plant was grounded and extracted with methanol to prepare methanol crud extract. In vitro biological tests were conducted using this methanolic extracts according to the standard procedure. 100% death rate of brine shrimp was perceived at 3 mg/mL of plant extract after 72 hours. The extract showed action against Aspergillus flavius i.e. 90% followed by A. niger (91%) while the highest activity was shown against A. fumegatrus (94%). Important scavenging results were detected during scavenging of free radicals viz; 92.2% against DPPH, 82.2% to ABTS, 75.8% to hydrogen peroxide, 88.1% to ?-carotene, 86.1% to hydroxyl radical and 89.4% against phosphomolybdate at 3 mg/mL were obtained. The results obtained in this study point out that extract showed significant biological activities which might be due to the presence of bioactive constituents.

Details

Language :
English
ISSN :
19910088
Volume :
11
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Bangladesh Journal of Pharmacology
Publication Type :
Academic Journal
Accession number :
edsdoj.69ca0251181b41629fcd3db6a4f4a2ed
Document Type :
article
Full Text :
https://doi.org/10.3329/bjp.v11i2.23611