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Hand hygiene: virucidal efficacy of a liquid hand wash product against Ebola virus

Hand hygiene: virucidal efficacy of a liquid hand wash product against Ebola virus

Authors :
T.A. Cutts
R.W. Nims
S.S. Theriault
E. Bruning
J.R. Rubino
M.K. Ijaz
Source :
Infection Prevention in Practice, Vol 3, Iss 1, Pp 100122- (2021)
Publication Year :
2021
Publisher :
Elsevier, 2021.

Abstract

Summary: Background: Hand washing is an important targeted hygiene intervention for limiting the spread of infectious agents, including the Ebola virus, which continues to re-emerge. We have assessed the virucidal efficacy of a commercially available liquid hand wash product (LHW) for inactivating Ebola virus. Methods: The ASTM E1052-11 Standard was used to evaluate the efficacy of an LHW containing the microbicidal active salicylic acid for inactivating Ebola virus - Makona variant suspended in an organic load. Three concentrations (12.5%, 25%, 50%) of three lots of LHW prepared in 440 ppm hard water were evaluated at room temperature for 20, 30, and 60 s contact time. Results: A 25% solution of the LHW caused 4.5 log10 and 4.8 log10 reduction in Ebola virus titer within 20 and 30 s, respectively. The efficacy of a 12.5% LHW solution was lower (1.9 and 2.0 log10 reduction in titer within 20 and 30 s, respectively). The efficacy of the 50% LHW solution could not be measured, due to inability to sufficiently neutralize the LHW at the end of exposure. Conclusion: These results suggest the potential utility of an appropriately formulated liquid hand wash agent during Ebola virus disease outbreaks for use within healthcare, community, and home settings. Such an LHW should also be effective against other enveloped viruses, such as the pandemic coronavirus SARS-CoV-2.

Details

Language :
English
ISSN :
25900889
Volume :
3
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Infection Prevention in Practice
Publication Type :
Academic Journal
Accession number :
edsdoj.69b168aabdd143c0ac23fd14e913bac2
Document Type :
article
Full Text :
https://doi.org/10.1016/j.infpip.2021.100122