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Clinical Study on the Prognosis of Patients with Thymoma with Myasthenia Gravis

Authors :
Dongfeng YUAN
Zhitao GU
Guanghui LIANG
Wentao FANG
Yin LI
Chinese Alliance for Research of Thymoma Database
Source :
Chinese Journal of Lung Cancer, Vol 21, Iss 1, Pp 1-7 (2018)
Publication Year :
2018
Publisher :
Chinese Anti-Cancer Association; Chinese Antituberculosis Association, 2018.

Abstract

Background and objective Thymoma is frequently associated with myasthenia gravis (MG). However, whether MG is a factor for the outcome of patients with thymoma following complete thymectomy remains unknown. The aim of this study is to investigate the effect of thymoma with MG prognostic factors. Methods A retrospective analysis of The Chinese Alliance for Research in Thymomas (ChART) database within 1992-2012 complete cases 875 cases, 20 years follow-up data analysis thymic tumor tissue type credits and MG, Masaoka staging and prognosis, postoperative adjuvant therapy and relationship with the prognosis of surgical removal of the way. Results Thymic tumor tissue type credit has correlation with MG, difference was statistically significant (χ2=24.908, P B3 type (65/239, 27.20%) > B1 (27/132, 20.45%) > AB (43/267, 16.10%) > type A, 10.17% (6/59), Masaoka stage has no correlation with MG (χ2=0.365, P=1.365). Survival analysis showed that the WHO classification, Masaoka stage associated with prognosis (P

Details

Language :
Chinese
ISSN :
10093419 and 19996187
Volume :
21
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Chinese Journal of Lung Cancer
Publication Type :
Academic Journal
Accession number :
edsdoj.695df87dd945424583a121551888e44b
Document Type :
article
Full Text :
https://doi.org/10.3779/j.issn.1009-3419.2018.01.01