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Evaluation of interleukin-6 concentration in the liver of Albino Swiss mice after intoxication with various doses of patulin

Authors :
Borzecki Pawel
Borzecka Agnieszka
Chylinska-Wrzos Patrycja
Lis-Sochocka Marta
Wawryk-Gawda Ewelina
Jodlowska-Jedrych Barbara
Source :
Current Issues in Pharmacy and Medical Sciences, Vol 32, Iss 1, Pp 34-39 (2019)
Publication Year :
2019
Publisher :
Sciendo, 2019.

Abstract

Patulin is a mycotoxin produced by many species of the fungi. The toxic action of patulin mainly affects the gastrointestinal tract and the immune system. The aim of our work was to assess the toxic effect of patulin, based on the analysis of interleukin IL-6 concentrations in the liver of test animals loaded with different doses of this mycotoxin. The research was conducted on mice which were assigned to 6 groups receiving different doses of active substances. After decapitation, their livers were taken for laboratory testing.

Details

Language :
English
ISSN :
2084980X and 23006676
Volume :
32
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Current Issues in Pharmacy and Medical Sciences
Publication Type :
Academic Journal
Accession number :
edsdoj.6938b7a98334b94a44c469de2c38229
Document Type :
article
Full Text :
https://doi.org/10.2478/cipms-2019-0008