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Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2–Associated Deaths

Authors :
Fabian Heinrich
Ann Sophie Schröder
Anna-Lina Gerberding
Moritz Gerling
Felicia Langenwalder
Philine Lange
Axel Heinemann
Eric Bibiza-Freiwald
Dominik Sebastian Nörz
Martin Aepfelbacher
Susanne Pfefferle
Benjamin Ondruschka
Marc Lütgehetmann
Source :
Emerging Infectious Diseases, Vol 28, Iss 1, Pp 244-247 (2022)
Publication Year :
2022
Publisher :
Centers for Disease Control and Prevention, 2022.

Abstract

We investigated the infectivity of 128 severe acute respiratory disease coronavirus 2–associated deaths and evaluated predictive values of standard diagnostic procedures. Maintained infectivity (20%) did not correlate with viral RNA loads but correlated well with anti-S antibody levels. Sensitivity >90% for antigen-detecting rapid diagnostic tests supports their usefulness for assessment.

Details

Language :
English
ISSN :
10806040 and 10806059
Volume :
28
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Emerging Infectious Diseases
Publication Type :
Academic Journal
Accession number :
edsdoj.685eb8d50ae4ce9891db7161401dffe
Document Type :
article
Full Text :
https://doi.org/10.3201/eid2801.211749