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Nucleated red blood cells explain most of the association between DNA methylation and gestational age

Authors :
Kristine L. Haftorn
William R. P. Denault
Yunsung Lee
Christian M. Page
Julia Romanowska
Robert Lyle
Øyvind E. Næss
Dana Kristjansson
Per M. Magnus
Siri E. Håberg
Jon Bohlin
Astanand Jugessur
Source :
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

CpG sites associated with gestational age are predominantly found in nucleated red blood cells, which point to an epigenetic signature of erythropoiesis as being partly responsible for this association.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
6
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.685ca7f611554c978bb43c19b97d8d3b
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-023-04584-w