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Levofloxacin prophylaxis and parenteral nutrition have a detrimental effect on intestinal microbial networks in pediatric patients undergoing HSCT

Authors :
Marco Fabbrini
Federica D’Amico
Davide Leardini
Edoardo Muratore
Monica Barone
Tamara Belotti
Maria Luisa Forchielli
Daniele Zama
Andrea Pession
Arcangelo Prete
Patrizia Brigidi
Simone Rampelli
Marco Candela
Silvia Turroni
Riccardo Masetti
Source :
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

A longitudinal characterization of the gut microbiome in 30 pediatric hematopoietic stem cell transplantation patients reveals that the combination of levofloxacin prophylaxis and parental nutrition disrupts gut microbiome networks.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
6
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.68266095b6094c2495b084513b6b7dfa
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-023-04436-7