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Elucidating the genetic architecture of reproductive ageing in the Japanese population

Authors :
Momoko Horikoshi
Felix R. Day
Masato Akiyama
Makoto Hirata
Yoichiro Kamatani
Koichi Matsuda
Kazuyoshi Ishigaki
Masahiro Kanai
Hollis Wright
Carlos A. Toro
Sergio R. Ojeda
Alejandro Lomniczi
Michiaki Kubo
Ken K. Ong
John. R. B. Perry
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

The timing of female reproductive capacity is influenced by genetic and environmental factors. Here, in genome-wide association studies, the authors identify genetic loci for age at menarche and onset of menopause in Japanese women, and highlight differences with European populations.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.66e1258d1fd84ee49edcd0abf3476652
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-04398-z