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Circulating Growth Differentiation Factor 15 Is Increased Preceding Preeclampsia Diagnosis: Implications as a Disease Biomarker
- Source :
- Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 16 (2021)
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Background We investigated the biomarker potential of growth differentiation factor 15 (GDF‐15), a stress response protein highly expressed in placenta, to predict preeclampsia. Methods and Results In 2 prospective cohorts (cohort 1: 960 controls, 39 women who developed preeclampsia; cohort 2: 950 controls, 41 developed preeclampsia), plasma concentrations of GDF‐15 at 36 weeks' gestation were significantly increased among those who developed preeclampsia (P
Details
- Language :
- English
- ISSN :
- 20479980
- Volume :
- 10
- Issue :
- 16
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.66a4629a4d3e44588e70e5f1551eddcf
- Document Type :
- article
- Full Text :
- https://doi.org/10.1161/JAHA.120.020302