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Gradient light interference microscopy for 3D imaging of unlabeled specimens

Authors :
Tan H. Nguyen
Mikhail E. Kandel
Marcello Rubessa
Matthew B. Wheeler
Gabriel Popescu
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

Challenges in biological imaging include labeling, photobleaching and phototoxicity, as well as light scattering. Here, Nguyen et al. develop a quantitative phase method that uses low-coherence interferometry for label-free 3D imaging in scattering tissue.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.65e37646af14d50945de891b9a135e7
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-00190-7