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Deep Learning Based Analysis of Breast Cancer Using Advanced Ensemble Classifier and Linear Discriminant Analysis

Authors :
Xinfeng Zhang
Dianning He
Yue Zheng
Huaibi Huo
Simiao Li
Ruimei Chai
Ting Liu
Source :
IEEE Access, Vol 8, Pp 120208-120217 (2020)
Publication Year :
2020
Publisher :
IEEE, 2020.

Abstract

In the recent past, the Classifiers are based on genetic signatures in which many microarray studies are analyzed to predict medical results for cancer patients. However, the Signatures from different studies have been benefitted with low-intensity ratio during the classification of individual datasets has been considered as a significant point of research in the present scenario. Hence to overcome the above-discussed issue, this paper provides a Deep Learning Framework that combines an algorithm of necessary processing of Linear Discriminant Analysis (LDA) and Auto Encoder (AE) Neural Network to classify different features within the profile of gene expression. Hence, an advanced ensemble classification has been developed based on the Deep Learning (DL) algorithm to assess the clinical outcome of breast cancer. Furthermore, numerous independent breast cancer datasets and representations of the signature gene, including the primary method, have been evaluated for the optimization parameters. Finally, the experiment results show that the suggested deep learning frameworks achieve 98.27% accuracy than many other techniques such as genomic data and pathological images with multiple kernel learning (GPMKL), Multi-Layer Perception (MLP), Deep Learning Diagnosis (DLD), and Spatiotemporal Wavelet Kinetics (SWK).

Details

Language :
English
ISSN :
21693536
Volume :
8
Database :
Directory of Open Access Journals
Journal :
IEEE Access
Publication Type :
Academic Journal
Accession number :
edsdoj.65d1d7a20ad447c39fba11ef3087255d
Document Type :
article
Full Text :
https://doi.org/10.1109/ACCESS.2020.3005228