Back to Search Start Over

Symptom prevalence of patients with fibrotic interstitial lung disease: a systematic literature review

Authors :
Sabrina Carvajalino
Carla Reigada
Miriam J. Johnson
Mendwas Dzingina
Sabrina Bajwah
Source :
BMC Pulmonary Medicine, Vol 18, Iss 1, Pp 1-11 (2018)
Publication Year :
2018
Publisher :
BMC, 2018.

Abstract

Abstract Background Those affected by advanced fibrotic interstitial lung diseases have limited treatment options and in the terminal stages, the focus of care is on symptom management. However, quantitatively, little is known about symptom prevalence. We aimed to determine the prevalence of symptoms in Progressive Idiopathic Fibrotic Interstitial Lung Disease (PIF-ILD). Methods Searches on eight electronic databases including MEDLINE for clinical studies between 1966 and 2015 where the target population was adults with PIF-ILD and for whom the prevalence of symptoms had been calculated. Results A total of 4086 titles were screened for eligibility criteria; 23 studies were included for analysis. The highest prevalence was that for breathlessness (54–98%) and cough (59–100%) followed by heartburn (25–65%) and depression (10–49%). The heterogeneity of studies limited their comparability, but many of the symptoms present in patients with other end-stage disease were also seen in PIF-ILD. Conclusions This is the first quantitative review of symptoms in people with Progressive Idiopathic Fibrotic Interstitial Lung Diseases. Symptoms are common, often multiple and have a comparable prevalence to those experienced in other advanced diseases. Quantification of these data provides valuable information to inform the allocation of resources.

Details

Language :
English
ISSN :
14712466
Volume :
18
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Pulmonary Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.6592295dd2ce4848b75954c6781d50eb
Document Type :
article
Full Text :
https://doi.org/10.1186/s12890-018-0651-3