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Clinical features of cardiac lesion in patients with generalized sarcoidosis
Clinical features of cardiac lesion in patients with generalized sarcoidosis
- Source :
- Терапевтический архив, Vol 90, Iss 1, Pp 54-59 (2018)
- Publication Year :
- 2018
- Publisher :
- "Consilium Medicum" Publishing house, 2018.
-
Abstract
- The article presents a clinical observation of two patients with generalized sarcoidosis. The woman typical granulomatous changes in the lungs and lymph nodes combined with atrial fibrillation, kidney failure and hereditary thrombophilia, men with atherosclerotic coronary arteries, re-myocardial infarction, cholestasis, tubulointerstitial nephritis. The accession of systemic manifestations was accompanied by increase of level of angiotensin-converting enzyme in the blood serum, morphological examination of lung tissue in both cases there were high histological activity of vasculitis and granulomatous inflammation. Extrapulmonary symptoms regressed when conducting immunosuppressive therapy. Discusses modern aspects of diagnosis of sarcoidosis in clinical practice.
Details
- Language :
- Russian
- ISSN :
- 00403660 and 23095342
- Volume :
- 90
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Терапевтический архив
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.6501c2acdb249d780f16af4d442c40f
- Document Type :
- article
- Full Text :
- https://doi.org/10.17116/terarkh201890154-59