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Early outcomes of experience warm surgery in children undergoing complete repair of tetralogy of Fallot in developing countries

Authors :
Alaa Mohamad Hussain
Mohammad Ali Younes
Source :
BMC Pediatrics, Vol 24, Iss 1, Pp 1-6 (2024)
Publication Year :
2024
Publisher :
BMC, 2024.

Abstract

Abstract Objectives While significant evidence supports the benefits of normothermic cardiopulmonary bypass (NCPB) over hypothermic techniques, many institutions in developing countries, including ours, continue to employ hypothermic methods. This study aimed to assess the early postoperative outcomes of normothermic cardiopulmonary bypass (NCPB) for complete surgical repair via the Tetralogy of Fallot (TOF) within our national context. Methods We conducted this study in the Pediatric Cardiac Intensive Care Unit (PCICU) at the University Children’s Hospital. One hundred patients who underwent complete TOF repair were enrolled and categorized into two groups: the normothermic group (n = 50, temperature 35–37 °C) and the moderate hypothermic group (n = 50, temperature 28–32 °C). We evaluated mortality, morbidity, and postoperative complications in the PCICU as outcome measures. Results The demographic characteristics were similar between the two groups. However, the cardiopulmonary bypass (CPB) time and aortic cross-clamp (ACC) time were notably longer in the hypothermic group. The study recorded seven deaths, yielding an overall mortality rate of 7%. No significant differences were observed between the two groups concerning mortality, morbidity, or postoperative complications in the PCICU. Conclusions Our findings suggest that normothermic procedures, while not demonstrably effective, are safe for pediatric cardiac surgery. Further research is warranted to substantiate and endorse the adoption of this technique.

Details

Language :
English
ISSN :
14712431
Volume :
24
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Pediatrics
Publication Type :
Academic Journal
Accession number :
edsdoj.64bd5e69c859430aa8bd96e70727e6f5
Document Type :
article
Full Text :
https://doi.org/10.1186/s12887-024-04976-9