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Prognostic value of platelet distribution width to lymphocyte ratio in patients with hepatocellular carcinoma following hepatectomy

Authors :
Zhi-Han Zhong
Lei Liang
Tian-Wei Fu
Mu-Gen Dai
Jian Cheng
Si-Yu Liu
Tai-Wei Ye
Guo-Liang Shen
Cheng-Wu Zhang
Dong-Sheng Huang
Jun-Wei Liu
Source :
BMC Cancer, Vol 23, Iss 1, Pp 1-8 (2023)
Publication Year :
2023
Publisher :
BMC, 2023.

Abstract

Abstract Background Platelet distribution width (PDW), but not platelet count, was found to more comprehensively reflect platelet activity. The present study, thus, aimed to evaluate the prognostic value of PDW to lymphocyte ratio (PDWLR) in patients with hepatocellular carcinoma (HCC) following hepatectomy. Methods Patients following hepatectomy were analyzed retrospectively. The Kaplan-Meier survival curves and Cox regression model were used to determine the prognostic value of PDWLR. Results 241 patients were analyzed eventually, and stratified into low and high PDWLR groups (≤ 9.66 vs. > 9.66). Results of comparing the baseline characteristics showed that high PDWLR was significantly associated with cirrhosis, and intraoperative blood loss (all P

Details

Language :
English
ISSN :
14712407
Volume :
23
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Cancer
Publication Type :
Academic Journal
Accession number :
edsdoj.64a6e51f72ca4f5397492083bcadfb84
Document Type :
article
Full Text :
https://doi.org/10.1186/s12885-023-11621-8