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Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival

Authors :
Megumi Shiota
Masayuki Naya
Takehiro Yamamoto
Takako Hishiki
Takeharu Tani
Hiroyuki Takahashi
Akiko Kubo
Daisuke Koike
Mai Itoh
Mitsuyo Ohmura
Yasuaki Kabe
Yuki Sugiura
Nobuyoshi Hiraoka
Takayuki Morikawa
Keiyo Takubo
Kentaro Suina
Hideaki Nagashima
Oltea Sampetrean
Osamu Nagano
Hideyuki Saya
Shogo Yamazoe
Hiroyuki Watanabe
Makoto Suematsu
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Surface-enhanced Raman spectroscopy (SERS) visualizes fingerprints of intermolecular vibrations of many metabolites. Here the authors report a SERS imaging technique that enables the visualization of metabolites distribution and automated extraction of tumour boundaries in frozen tissues.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.6370f21a7dce45e4b681376a2ad703d3
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-03899-1