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ASSESSMENT OF THE USE OF TRANEXAMIC ACID AFTER TOTAL KNEE ARTHROPLASTY
- Source :
- Acta Ortopédica Brasileira, Vol 28, Iss 2, Pp 74-77 (2020)
- Publication Year :
- 2020
- Publisher :
- Sociedade Brasileira de Ortopedia e Traumatologia, 2020.
-
Abstract
- ABSTRACT Objective: To evaluate the profile of blood loss and blood transfusions after the introduction of Tranexamic acid (TXA) in a tertiary university hospital in Brazil. Methods: 173 patients were retrospectively divided into two groups: the ones who received TXA and the control group. Hemoglobin levels (Hb), drain output, transfusion rates, and thromboembolic events were measured. Results: Among the patients included in this study, 82 cases received TXA. Blood transfusion occurred in 3 cases of the TXA group (3.7%), and in 27 control group cases (29.7%; p < 0.001). The average Hb decrease was 2.7 g/dl (± 1.39) and the median drain output was 270 mL in the TXA group. In the control group, the values were 3.41 g/dl (± 1.34; p < 0.001) and 460 mL (p < 0.001), respectively. Thromboembolic events occurred in 2 TXA group cases (2.4%) and in 3 control group cases (3.3%; p > 0.999). Conclusion: TXA was effective in reducing blood transfusion rates, Hb decrease, and drain output on the 1st postoperative day without increasing thromboembolic events. Level of evidence III, Retrospective comparative study.
Details
- Language :
- English, Portuguese
- ISSN :
- 14137852
- Volume :
- 28
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- Acta Ortopédica Brasileira
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.636fce3ddcbe4cf4bed787cd93bff7c7
- Document Type :
- article
- Full Text :
- https://doi.org/10.1590/1413-785220202802228410