Effect of periodic of resistance training on lipid peroxidation and Tumor necrosis factor-alpha in the heart tissue of male rats exposed to stanazol

Background and Aims: Nowadays, the use of energizing substances has become a complex complicated problem in sports and causes damage to various tissues., on the other hand However, sports activity has a significant impact on controlling and improving oxidative stress factors and inflammatory indicators. Therefore, this study aimed to investigate the effect of eight- weeks of resistance training on lipid peroxidation (malondialdehyde [MDA]MDA) and tumor necrosis factor-alpha (TNF-α) in the heart tissue of rats exposed to stanazol. Materials and Methods: In this experimental study, 24 male rats with a weight range of 150-200 g and a mean age of 8 weeks were selected and randomly divided into 4 groups (n=6 each), namely 1) control (C), 2) sham (Sh), 3) consumption of stanazol (S), and 4) consumption of stanazol together with resistance training (S+RT). During eight weeks, both groups of 3 and 4 received 5 mg/kg stanazol intraperitoneally daily; however, group 4 performed resistance training three times a week with an intensity of 30%-100% of their body weight. A one-way variance analysis and Tukey's post hoc test were used to analyze the data (P