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Insights into lipid metabolism and immune-inflammatory responses in the pathogenesis of coronary artery ectasia
- Source :
- Frontiers in Physiology, Vol 14 (2023)
- Publication Year :
- 2023
- Publisher :
- Frontiers Media S.A., 2023.
-
Abstract
- Coronary artery ectasia (CAE) is a rare finding that is associated with poor clinical outcomes (Kawsara et al. 2018), and disorders in lipid metabolism have been reported in CAE. Lipids constitute one of the three metabolite types that regulate bodily functions and are also powerful signaling molecules (Han 2016; Zhu et al. 2021) that affect immunoregulation and inflammatory responses via a series of transcription factors and signaling pathways (Barrera et al. 2013). Although abnormal lipid metabolism and immunoinflammatory responses have been reported in CAE, their roles in the pathogenic mechanisms underlying CAE are currently unclear.
Details
- Language :
- English
- ISSN :
- 1664042X
- Volume :
- 14
- Database :
- Directory of Open Access Journals
- Journal :
- Frontiers in Physiology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.631dbfb681aa4bdfa901b7417caca354
- Document Type :
- article
- Full Text :
- https://doi.org/10.3389/fphys.2023.1096991