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Fever, convulsions, and rash: a case report of neonatal lupus erythematosus with macrophage activation syndrome
- Source :
- Frontiers in Pediatrics, Vol 12 (2024)
- Publication Year :
- 2024
- Publisher :
- Frontiers Media S.A., 2024.
-
Abstract
- Neonatal lupus erythematosus (NLE) is a rare acquired autoimmune disease associated with the entry of maternal antibodies into the fetal circulation via the placenta during pregnancy. Macrophage activation syndrome (MAS) is a severe hyperinflammatory disease. Herein, we present a case of NLE with MAS accompanied by fever, convulsions, and rash. High-dose gamma globulin and non-shock doses of steroids can be used as a first-line treatment for NLE with MAS. Fever can be a clinical manifestation of NLE, especially cutaneous lupus. Rash recession could be used to judge whether the disease is effectively controlled by treatment.
- Subjects :
- neonatal lupus
fever
rash
macrophage activation syndrome
treatment
Pediatrics
RJ1-570
Subjects
Details
- Language :
- English
- ISSN :
- 22962360
- Volume :
- 12
- Database :
- Directory of Open Access Journals
- Journal :
- Frontiers in Pediatrics
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.630f893e3abf41858647aa61546e0144
- Document Type :
- article
- Full Text :
- https://doi.org/10.3389/fped.2024.1381493