Back to Search
Start Over
Genomic susceptibility to gastric cancer in Northwest Iran: population-based and case–control studies
- Source :
- Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-15 (2024)
- Publication Year :
- 2024
- Publisher :
- SpringerOpen, 2024.
-
Abstract
- Abstract Introduction The age-standardized incidence rate for gastric cancer is estimated to be 11.1% worldwide and 39.1% for Ardabil province in northwest Iran. Single nucleotide polymorphisms (SNPs) occur in coding and non-coding regions, contributing to cancer susceptibility. To identify SNPs predisposing individuals to gastric cancer in this region, we compared 263 variants between the Ardabil population and other populations. Materials and methods Whole exome sequencing was used to determine the distribution of variants in the genomic DNA of 150 volunteers (aged
- Subjects :
- Medicine (General)
R5-920
Genetics
QH426-470
Subjects
Details
- Language :
- English
- ISSN :
- 20902441
- Volume :
- 25
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Egyptian Journal of Medical Human Genetics
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.6260a9ce70714bd3856ea197bbaa3dbf
- Document Type :
- article
- Full Text :
- https://doi.org/10.1186/s43042-024-00474-w