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Structural remodelling of the carbon–phosphorus lyase machinery by a dual ABC ATPase

Authors :
Søren K. Amstrup
Sui Ching Ong
Nicholas Sofos
Jesper L. Karlsen
Ragnhild B. Skjerning
Thomas Boesen
Jan J. Enghild
Bjarne Hove-Jensen
Ditlev E. Brodersen
Source :
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

Here, authors analyse the structural organisation of the large carbon-phosphorus lyase enzyme from bacteria using electron microscopy and discover that it contains two ATP-binding cassette dimers of PhnK and PhnL and opens upon ATP hydrolysis.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.625657f8909c41b5bade23dc3d832d87
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-023-36604-y