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Can we treat secondary progressive multiple sclerosis now?

Authors :
Rohit Bhatia
Nishita Singh
Source :
Annals of Indian Academy of Neurology, Vol 22, Iss 2, Pp 131-136 (2019)
Publication Year :
2019
Publisher :
Wolters Kluwer Medknow Publications, 2019.

Abstract

Secondary progressive multiple sclerosis (SPMS) is characterized by progressive accumulation of disability without intermittent recovery. Treatment of these patients is challenging due to limited understanding of pathogenesis and fewer therapeutic options. This article summarizes difficulties in defining and conducting trials in SPMS, review major clinical trials on therapies approved and unapproved in SPMS and lastly, therapies in pipeline for use in SPMS.

Details

Language :
English
ISSN :
09722327 and 19983549
Volume :
22
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Annals of Indian Academy of Neurology
Publication Type :
Academic Journal
Accession number :
edsdoj.61d5349dce294758bb2c9b12fdd168d0
Document Type :
article
Full Text :
https://doi.org/10.4103/aian.AIAN_345_18