FEATURES OF THE HEMOMICROCIRCULATION OF THE EYE CONJUCTIVA IN WOMEN WITH THE METABOLIC SYNDROME

The increasing prevalence of metabolic syndrome and the increase in the number of surgical interventions in the face prompted us to study the impact of metabolic syndrome on the healing processes of thewound surface and complications after planned plastic surgery. One of the reasons for this may be a change in the hemomicrocirculatory channel of the skin. Since the vessels of the bulbar conjunctiva originate from the branches of the internal carotid artery, and the blood supply of the facial skin is also provided by the branches of the internal carotid artery, it was concluded that changes in the microcirculation of the conjunctiva of the eye will correlate with changes in the microcirculation of the skin. The aim of the work was to study the characteristics of hemomicrocirculation of the conjunctiva of the eye in women with metabolic syndrome. 60 women age from 39 to 55 years who apply surgical help for cosmetic skin defects were examined. The control group consisted of 30 almost healthy women. Manifestations of metabolic syndrome (insulin resistance, hypertension, body mass index > 30 kg/m2, increased triglycerides and decreased high-density lipoproteins) were registered in 30 women who were included in the main group. The study of the hemomicrocirculation of the bulbar conjunctiva was carried out with the help of vital microscopy using a Zeiss SL 160 slit lamp (Germany) with a magnification from 5 to 50 times according to the methodology approved by the Ministry of Health of Ukraine. In women with metabolic syndrome, were found significant changes in the hemomicrocirculation of the bulbar conjunctiva of the eye, which was manifested in a violation of the parallelism of the arrangement of microvessels, a significant increase in the frequency of detection of microaneurysms, the development of myogenic dystrophy, and an increase in the number of patients with signs of vascular dystonia and structural rearrangement of microvessels, an increase in the number of patients with arteriolo-venular anastomoses and significant and irreversible trophic disturbances in the bulbar conjunctiva in most patients, an increase in the number of patients with structural remodeling of the vascular bed and with fresh extravasates and hemosiderin deposition, dystonia of microvessels and precapillary sphincters. Violations of blood flow in capillaries with a diameter of 3-5 microns and the presence of thrombosis in them were also detected. Since the blood supply of the conjunctiva of the eye is carried out by the branches of the internal carotid artery, it is concluded that the microcirculation is disrupted not only at the level of the organism as a whole, but also in the skin, in particular.