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Phenytoin-induced cerebellar atrophy: A case for reversibility of neurological decline

Authors :
Edwin Mogere
Davis Cheruiyot
Manakhe Nassiuma
Source :
Radiology Case Reports, Vol 19, Iss 1, Pp 442-444 (2024)
Publication Year :
2024
Publisher :
Elsevier, 2024.

Abstract

This case serves as a reminder of the infrequent, yet consequential occurrence of cerebellar degeneration linked to phenytoin usage. Whilst emphasizes the importance of monitoring patients on long-term phenytoin therapy, and it further suggests considering employing bedside imaging tools such as Ultrasound fusion imaging for follow-up of patients at risk of this type of disorder. We present a case study involving a 23-year-old woman who experienced significant neurological impairment resulting in severe cerebellar atrophy while undergoing phenytoin treatment. On cessation of phenytoin, the patient exhibited improvement with enhanced cerebellar function.

Details

Language :
English
ISSN :
19300433
Volume :
19
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Radiology Case Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.61966f0fb1da401483efb545f75e18c0
Document Type :
article
Full Text :
https://doi.org/10.1016/j.radcr.2023.10.064