Back to Search Start Over

GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21

Authors :
Joseph L. Wiemels
Kyle M. Walsh
Adam J. de Smith
Catherine Metayer
Semira Gonseth
Helen M. Hansen
Stephen S. Francis
Juhi Ojha
Ivan Smirnov
Lisa Barcellos
Xiaorong Xiao
Libby Morimoto
Roberta McKean-Cowdin
Rong Wang
Herbert Yu
Josephine Hoh
Andrew T. DeWan
Xiaomei Ma
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Childhood acute lymphoblastic leukemia is common in Latino Americans. Here, the authors conduct a genome-wide association study in a Californian cohort containing children of Latino heritage, and identify loci on 17q12 and 8q24 which may affect hematopoietic and growth-regulation pathways.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.60897a19a3c545a48ff596841e051402
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-02596-9