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The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly

Authors :
Mark Pinese
Paul Lacaze
Emma M. Rath
Andrew Stone
Marie-Jo Brion
Adam Ameur
Sini Nagpal
Clare Puttick
Shane Husson
Dmitry Degrave
Tina Navin Cristina
Vivian F. S. Kahl
Aaron L. Statham
Robyn L. Woods
John J. McNeil
Moeen Riaz
Margo Barr
Mark R. Nelson
Christopher M. Reid
Anne M. Murray
Raj C. Shah
Rory Wolfe
Joshua R. Atkins
Chantel Fitzsimmons
Heath M. Cairns
Melissa J. Green
Vaughan J. Carr
Mark J. Cowley
Hilda A. Pickett
Paul A. James
Joseph E. Powell
Warren Kaplan
Greg Gibson
Ulf Gyllensten
Murray J. Cairns
Martin McNamara
Marcel E. Dinger
David M. Thomas
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Healthspan and healthy aging are areas of research with potential socioeconomic impact. Here, the authors present the Medical Genome Reference Bank (MGRB) which consist of over 4,000 individuals aged 70 years and older without a history of the major age-related diseases and report on results from whole-genome sequencing and association analyses.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.606fe68d7d054718aee8c708231ad376
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-14079-0