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Left ventricular longitudinal systolic dysfunction is associated with right atrial dyssynchrony in heart failure with preserved ejection fraction

Authors :
Ibadete Bytyçi
Edmond Haliti
Gëzim Berisha
Arbërie Tishukaj
Faik Shatri
Gani Bajraktari
Source :
Revista Portuguesa de Cardiologia, Vol 35, Iss 4, Pp 207-214 (2016)
Publication Year :
2016
Publisher :
Elsevier, 2016.

Abstract

Objective: We aimed in this study to assess the role of longitudinal left ventricular (LV) systolic function in heart failure with preserved ejection fraction (HFpEF) in delayed intra- and interatrial conduction time. Methods: In 85 consecutive patients with HFpEF (age 60±11 years, ejection fraction [EF] ≥45%), a complete M-mode echocardiographic and tissue Doppler imaging (TDI) study was performed. The times from the onset of the P wave on the ECG to the beginning of the A′ wave (PA) from the lateral and septal mitral and tricuspid annuli on TDI were recorded. The difference between these intervals gave the intra- and interatrial dyssynchrony. Based on mitral annular plane systolic excursion (MAPSE), patients were classified as having HFpEF with impaired (MAPSE ≤1.2 cm) or normal (MAPSE >1.2 cm) longitudinal systolic function. Results: Patients with impaired MAPSE were older (p 1,2 cm). Resultados: Os doentes com ESPAM baixa eram mais velhos (p < 0,001), tinham índice de massa VE mais elevado (p < 0,001), volume auricular esquerdo (VAE) superior (p = 0,007), FE auricular esquerda (AE) mais baixa (p < 0,001), rácio E/e’ mais elevado (p = 0,002), onda e’ lateral e septal reduzidas (p = 0,005 e p = 0,006), onda tricúspide PA prolongada (p = 0,03) e aumento significativo da dessincronia da aurícula direita (AD) (p = 0,001), quando comparados com doentes com ESPAM normal. A ESPAM estava correlacionada com a dessincronia AD (r = -0,40, p < 0,001), mas não com a dessincronia interauricular e da AE. Conclusão: Nos doentes com ICFEp e ESPAM baixa, existe dessincronia AD, quando comparada com os doentes com ESPAM normal. Como os doentes com dessincronia AD têm risco mais elevado de arritmia, a avaliação desta dessincronia pode ajudar a melhorar o tratamento, bem como a auxiliar na previsão prognóstica destes doentes. Keywords: Heart failure, Right atrial dyssynchrony, Systolic longitudinal function, Palavras-chave: Insuficiência cardíaca, Dessincronia auricular direita, Função sistólica longitudinal

Details

Language :
English, Portuguese
ISSN :
08702551
Volume :
35
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Revista Portuguesa de Cardiologia
Publication Type :
Academic Journal
Accession number :
edsdoj.603d54280b4c1eaae7b45d37a231af
Document Type :
article
Full Text :
https://doi.org/10.1016/j.repc.2015.11.011