Methods for assessment of the course of wound process

Summary: The article is devoted to the analysis of methods for evaluation of the course of wound process. The problem of the treatment of wounds of various etiology is one of the complex sections of clinical medicine. Currently, there is an increase in the proportion of traumatic injuries that can cause wounds. Also common are vascular diseases and endocrine pathology, associated with the development of complications with the formation of tissue defects. The presence of tissue destruction and an infectious agent in the wound determine the development of purulent-inflammatory process in it. The current direction is determination of the criteria for diagnosis and methods of prevention of general and local complications. The purpose of the study was to determine the clinical and laboratory parameters used to reveal the stage of the wound process and to predict the development of complications. The factors that determine the wound healing process and the appropriate techniques for assessing the wound process were studied. Subjective and objective methods are identified among the control methods. The article describes techniques that reflect the condition of tissues forming the wound walls or wound surface; techniques enabling to characterize bacterial flora by qualitative and quantitative indicators; methods allowing to determine the state of local and general body resistance. A brief description of standard techniques – cytological examination of wound exudate, assessment of cytograms, planimetric and bacteriological tests – is given. The data on determination of pH of wound medium and liquid volumetric vulnerometry, estimation of the state of granulation tissue are given. The value of the use of computerized diagnostics and computerized monitoring of the wound process was studied. The importance of methods for objective assessment of the course of the wound process for control of the treatment efficacy and in experimental studies during preclinical trials of medicinal products and medical devices has been demonstrated.