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Pleomorphic adenoma with extensive squamous metaplasia and keratin cyst formations in minor salivary gland: a case report
- Source :
- Journal of Applied Oral Science, Vol 19, Iss 2, Pp 182-188 (2011)
- Publication Year :
- 2011
- Publisher :
- University of São Paulo, 2011.
-
Abstract
- Pleomorphic adenoma (PA), the most common salivary gland tumor, accounts for 54 to 65% of all salivary gland neoplasias and 80% of the benign salivary gland tumors. It most frequently affects the parotid gland, followed by the submandibular and the minor salivary glands. Microscopically, mucous, sebaceous, oncocytic and squamous metaplasia, sometimes with the formation of keratin pearls, may be present, but the latter rarely results in the formation of extensive keratin-flled cysts lined by squamous epithelium. Extensive squamous metaplasia can be mistaken for malignancy, including mucoepidermoid carcinoma and squamous cell carcinoma. Here, we present an unusual case of PA with extensive squamous metaplasia and keratin cyst formations in a minor salivary gland, and discuss its microscopic features, including the immunohistochemical characteristics, and differential diagnosis of this uncommon presentation.
- Subjects :
- Pleomorphic adenoma
Diagnosis
Salivary gland neoplasms
Dentistry
RK1-715
Subjects
Details
- Language :
- English
- ISSN :
- 16787757 and 16787765
- Volume :
- 19
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of Applied Oral Science
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5f3df347dab945cb82d39242af51e039
- Document Type :
- article
- Full Text :
- https://doi.org/10.1590/S1678-77572011000200016