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Dexamethasone and lactoferrin induced PMN-MDSCs relieved inflammatory adverse events of anti-cancer therapy without tumor promotion

Authors :
Xing Li
Jie Chen
Yong-Jian Chen
Yi-Dan Qiao
Li-Yun Zhao
Nan Jiang
Xiang-Yuan Wu
Yan-Fang Xing
Source :
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Li et al. show that dexamethasone and lactoferrin induced polymorphonuclear myeloid-derived suppressor cells relieve inflammatory conditions in mouse models with minimal effect on tumour growth. This work demonstrates promise for combating inflammatory adverse events during anti-cancer treatments.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
4
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.5f0da4bd4164d039b55198c4e4188a9
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-021-01769-z