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The interhemispheric CA1 circuit governs rapid generalisation but not fear memory

Authors :
Heng Zhou
Gui-Jing Xiong
Liang Jing
Ning-Ning Song
De-Lin Pu
Xun Tang
Xiao-Bing He
Fu-Qiang Xu
Jing-Fei Huang
Ling-Jiang Li
Gal Richter-Levin
Rong-Rong Mao
Qi-Xin Zhou
Yu-Qiang Ding
Lin Xu
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

Previous work has documented a slow form of memory generalization although a rapid one is demanded. Here the authors elucidate the role of the interhemispheric CA1-CA1 projection in a form of rapid generalization of contextual fear memory via gradual potentiation of these synapses over 24 h.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.5ed1ddb41cb43e79446c71a5ce434d3
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-02315-4