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Malignant pleural mesothelioma with constrictive pericarditis as the first manifestation: A case report

Authors :
Cheng‐Peng He
Di‐Wei Tu
Ting‐Wei Zhang
Qian Zhang
Qiang Zhang
Di Kang
Ying‐Ying Wang
Ying‐Ying Li
Bin Zhang
Sha‐Sha Han
Hong‐Bo Li
Source :
Clinical Case Reports, Vol 11, Iss 6, Pp n/a-n/a (2023)
Publication Year :
2023
Publisher :
Wiley, 2023.

Abstract

Abstract Pleural mesothelioma (PM) with pericardial involvement is extremely rare. We now report a rare case of malignant PM with constrictive pericarditis as the first presentation. A 59‐year‐old male diagnosed with constrictive pericarditis underwent pericardiectomy and pericardial pathology revealed mesothelial hyperplasia. Eight months after surgery, the patient was admitted to the hospital with chest tightness and wheezing for 5 days. Computed tomography scan of the chest showed a left lung expansion insufficiency, limited bilateral pleural thickening, pericardial thickening with a small amount of pericardial effusion, and multiple enlarged lymph nodes in the mediastinum, bilateral supraclavicular fossa, bilateral cervical roots, and right axilla. The pleural malignancy should be possibly considered. Pathology after pleural puncture showed malignant PM. Pathology after left supraclavicular lymph node puncture biopsy showed metastatic malignant mesothelioma. The diagnosis of this patient was clear. Although malignant PM rarely involves the pericardial constriction, we cannot ignore the fact that malignant PM involves the pericardium. The patient has been diagnosed with constrictive pericarditis, accompanied by pleural thickening and pleural effusion. Without other pathogenic factors, pleural biopsy should be aggressively performed in patients with constrictive pericarditis to determine the cause.

Details

Language :
English
ISSN :
20500904
Volume :
11
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Clinical Case Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.5e85cba2e5e8454cadb58f3b21465278
Document Type :
article
Full Text :
https://doi.org/10.1002/ccr3.7555