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Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability
- Source :
- Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
- Publication Year :
- 2017
- Publisher :
- Nature Portfolio, 2017.
-
Abstract
- Japanese encephalitis virus (JEV) is a Flavivirus responsible for thousands of deaths every year for which there are no specific anti-virals. Here, Wang et al. report the cryo-EM structure of mature JEV at near-atomic resolution and identify structural elements that modulate stability and virulence.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 8
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5e43459e464ee6a6602a849e5c6e81
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-017-00024-6