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Pancytopenia in a 70-Year-Old African-American Male: An Unusual Presentation of a Rare Disease
- Source :
- Case Reports in Hematology, Vol 2014 (2014)
- Publication Year :
- 2014
- Publisher :
- Wiley, 2014.
-
Abstract
- Hairy cell leukemia is a rare lymphoid neoplasm arising from mature B-lymphocytes. Clinically, the disease presents with splenomegaly and abdominal discomfort, frequent infections, fatigue and bleeding because of related cytopenias. Bone marrow biopsy is essential for diagnosis. Below we describe a case of a 70-year-old African-American male who presented to our hematology clinic complaining of fatigue. Clinical exam and computed tomography imaging did not reveal splenic enlargement. Blood work-up revealed pancytopenia and bone marrow was diagnostic for hairy cell leukemia.The patient was started on cladribine, with gradual improvement of his symptoms and blood count abnormalities. Therefore, it is essential to keep hairy cell leukemia in the differential of pancytopenia even in the absence of a splenomegaly.
- Subjects :
- Diseases of the blood and blood-forming organs
RC633-647.5
Subjects
Details
- Language :
- English
- ISSN :
- 20906560 and 20906579
- Volume :
- 2014
- Database :
- Directory of Open Access Journals
- Journal :
- Case Reports in Hematology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5d40e93928db4119ba5d0b67d2ac406d
- Document Type :
- article
- Full Text :
- https://doi.org/10.1155/2014/354810