Ratio of waist circumference to body mass index: A novel predictor of clinical outcome in hypertension patients

Abstract We aim to investigate the influence of waist circumference and body mass index (BMI) on all‐cause death and cardiovascular‐specific death in patients with hypertension. This prospective cohort study, based on waist circumference and body mass index measurements in patients with hypertension, provided risk estimates of all‐cause mortality and cardiovascular events. The waist circumference‐to‐BMI ratio (WtBR) is an anthropometric measure integrating waist circumference and BMI. We utilized multivariable Cox regression analysis, restricted cubic spline model, Kaplan‐Meier plot, random forest analysis, and sensitivity analysis to assess the relationship of WtBR with all‐cause mortality. Subsequently, Fine‐Gray competing risk regression models were applied to precisely evaluate the probability of cardiovascular‐specific death attributed to high WtBR. The results indicate that thea deceased group showed significantly higher WtBR and lower BMI compared with the alive groups (P