Back to Search
Start Over
RETFound-enhanced community-based fundus disease screening: real-world evidence and decision curve analysis
- Source :
- npj Digital Medicine, Vol 7, Iss 1, Pp 1-9 (2024)
- Publication Year :
- 2024
- Publisher :
- Nature Portfolio, 2024.
-
Abstract
- Abstract Visual impairments and blindness are major public health concerns globally. Effective eye disease screening aided by artificial intelligence (AI) is a promising countermeasure, although it is challenged by practical constraints such as poor image quality in community screening. The recently developed ophthalmic foundation model RETFound has shown higher accuracy in retinal image recognition tasks. This study developed an RETFound-enhanced deep learning (DL) model for multiple-eye disease screening using real-world images from community screenings. Our results revealed that our DL model improved the sensitivity and specificity by over 15% compared with commercial models. Our model also shows better generalisation ability than AI models developed using traditional processes. Additionally, decision curve analysis underscores the higher net benefit of employing our model in both urban and rural settings in China. These findings indicate that the RETFound-enhanced DL model can achieve a higher net benefit in community-based screening, advocating its adoption in low- and middle-income countries to address global eye health challenges.
- Subjects :
- Computer applications to medicine. Medical informatics
R858-859.7
Subjects
Details
- Language :
- English
- ISSN :
- 23986352
- Volume :
- 7
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- npj Digital Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5c868bd1f9284ec0ae7b7a812e270571
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41746-024-01109-5