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Facile Synthesis of Sulfonyl Chlorides/Bromides from Sulfonyl Hydrazides
- Source :
- Molecules, Vol 26, Iss 18, p 5551 (2021)
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- A simple and rapid method for efficient synthesis of sulfonyl chlorides/bromides from sulfonyl hydrazide with NXS (X = Cl or Br) and late-stage conversion to several other functional groups was described. A variety of nucleophiles could be engaged in this transformation, thus permitting the synthesis of complex sulfonamides and sulfonates. In most cases, these reactions are highly selective, simple, and clean, affording products at excellent yields.
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 26
- Issue :
- 18
- Database :
- Directory of Open Access Journals
- Journal :
- Molecules
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5b476fc21ab141dc81e61d7057ad539b
- Document Type :
- article
- Full Text :
- https://doi.org/10.3390/molecules26185551