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Facile Synthesis of Sulfonyl Chlorides/Bromides from Sulfonyl Hydrazides

Authors :
Rongxiang Chen
Shaohong Xu
Fumin Shen
Canran Xu
Kaikai Wang
Zhanyong Wang
Lantao Liu
Source :
Molecules, Vol 26, Iss 18, p 5551 (2021)
Publication Year :
2021
Publisher :
MDPI AG, 2021.

Abstract

A simple and rapid method for efficient synthesis of sulfonyl chlorides/bromides from sulfonyl hydrazide with NXS (X = Cl or Br) and late-stage conversion to several other functional groups was described. A variety of nucleophiles could be engaged in this transformation, thus permitting the synthesis of complex sulfonamides and sulfonates. In most cases, these reactions are highly selective, simple, and clean, affording products at excellent yields.

Details

Language :
English
ISSN :
14203049
Volume :
26
Issue :
18
Database :
Directory of Open Access Journals
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
edsdoj.5b476fc21ab141dc81e61d7057ad539b
Document Type :
article
Full Text :
https://doi.org/10.3390/molecules26185551