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PYK2 senses calcium through a disordered dimerization and calmodulin-binding element

Authors :
Afaque A. Momin
Tiago Mendes
Philippe Barthe
Camille Faure
SeungBeom Hong
Piao Yu
Gress Kadaré
Mariusz Jaremko
Jean-Antoine Girault
Łukasz Jaremko
Stefan T. Arold
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Protein tyrosine kinase 2-beta is shown to function as a sensor and effector of cellular calcium influx through self-association.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.5b021a3305b042d591ae0970768c1e8c
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03760-8